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Chapter 1: Homeostasis
Introduction
Homeostasis is the maintenance of internal environment of the body within narrow limits. It involves regulation of:
- Body temperature
- Blood glucose concentration
- Water balance
- pH of blood
Osmoregulation
Regulation of water and salt content in blood.
- Too much water: More urine production (dilute)
- Too little water: Less urine production (concentrated)
Thermoregulation
Body temperature maintained at 37°C.
- Hot: Sweating, vasodilation
- Cold: Shivering, vasoconstriction
Excretory System
Kidneys filter blood and remove waste.
- Kidneys: Filter blood, produce urine
- Ureters: Carry urine to bladder
- Bladder: Stores urine
- Urethra: Removes urine from body
Nephron
Functional unit of kidney.
- Glomerular Filtration: Blood filtered at Bowman's capsule
- Selective Reabsorption: Useful substances reabsorbed
- Urine Formation: Waste excreted
Chapter 2: Coordination and Control
Nervous System
Fast response system using electrical impulses.
Central Nervous System (CNS)
- Brain: Control center
- Spinal Cord: Reflex actions
Peripheral Nervous System (PNS)
- Somatic: Voluntary actions
- Autonomic: Involuntary actions
Neuron Structure
- Cell Body: Contains nucleus
- Dendrites: Receive signals
- Axon: Carries signal
- Myelin Sheath: Insulates axon
Synapse
Junction between two neurons. Neurotransmitters carry signal across.
Reflex Action
Rapid, automatic response to stimulus.
Example: Touching hot object → Hand pulls away instantly
Endocrine System
Slow response system using hormones.
Major Glands
- Pituitary: Master gland
- Thyroid: Metabolism, growth
- Pancreas: Insulin, glucagon (blood sugar)
- Adrenal: Fight or flight
- Gonads: Sex hormones
Chapter 3: Support and Movement
Skeletal System
Provides framework, protection, and enables movement.
Types of Bones
- Long Bones: Femur, humerus
- Short Bones: Carpals, tarsals
- Flat Bones: Skull, ribs
- Irregular Bones: Vertebrae
Bone Structure
- Compact Bone: Outer layer, hard
- Spongy Bone: Inner layer, contains marrow
- Bone Marrow: Red (blood cells) and yellow (fat)
Joints
- Ball and Socket: Hip, shoulder (all directions)
- Hinge: Knee, elbow (one plane)
- Pivot: Neck (rotation)
- Gliding: Wrist, ankle
Muscles
3 types: Skeletal (voluntary), Cardiac (heart), Smooth (involuntary).
Muscle Contraction
Actin and myosin filaments slide past each other (sliding filament theory).
Chapter 4: Inheritance
Genetics
Study of heredity and variation.
Key Terms
- Gene: Unit of heredity
- Allele: Different forms of a gene
- Genotype: Genetic makeup
- Phenotype: Physical appearance
- Homozygous: Same alleles (AA, aa)
- Heterozygous: Different alleles (Aa)
Mendel's Laws
Law of Dominance
In heterozygote, dominant allele masks recessive.
Law of Segregation
Alleles separate during gamete formation.
Law of Independent Assortment4>
Genes on different chromosomes assort independently.
Mendelian Ratio
- Monohybrid: 3:1 (dominant:recessive)
- Dihybrid: 9:3:3:1
Sex Determination
XX = Female | XY = Male
Genetic Disorders
- Down Syndrome: Extra chromosome 21
- Hemophilia: Blood clotting disorder (X-linked)
- Color Blindness: X-linked recessive
Chapter 5: Evolution
Theory of Evolution
Life on Earth has changed over time through gradual modifications.
Evidence of Evolution
- Fossils: Remains in rocks
- Comparative Anatomy: Homologous structures
- Embryology: Similar embryonic development
- Biochemistry: Common genetic code
Natural Selection
Darwin's theory: Organisms best adapted to environment survive and reproduce.
Speciation
Formation of new species from existing ones.
Human Evolution
- Australopithecus
- Homo habilis
- Homo erectus
- Homo neanderthalensis
- Homo sapiens (Modern humans)
Chapter 6: Ecosystem
Ecosystem Components
Biotic (Living)
- Producers: Plants (photosynthesis)
- Consumers: Herbivores, carnivores, omnivores
- Decomposers: Fungi, bacteria
Abiotic (Non-Living)
- Sunlight
- Water
- Temperature
- Soil
Food Chain and Web
Energy flows from producers → primary consumers → secondary consumers → tertiary consumers.
Energy Flow
Only 10% energy transferred to next trophic level
Biogeochemical Cycles
Carbon Cycle
- Photosynthesis: CO₂ → Organic compounds
- Respiration: Organic compounds → CO₂
- Decomposition: Releases carbon
Nitrogen Cycle
- Nitrogen fixation: N₂ → NH₃
- Nitrification: NH₃ → NO₂⁻ → NO₃⁻
- Denitrification: NO₃⁻ → N₂
Chapter 7: Biotechnology
Introduction
Use of living organisms or their products for human welfare.
Applications
1. Fermentation
- Bread making (yeast)
- Yogurt production (bacteria)
- Alcohol production
2. Genetic Engineering
- DNA Cloning: Copying genes
- PCR: Polymerase Chain Reaction
- Gene Therapy: Treating genetic diseases
3. Recombinant DNA Technology
Combining DNA from different sources.
Genetically Modified Organisms (GMOs)
- Plants: Pest-resistant, herbicide-tolerant
- Animals: Growth hormones
- Bacteria: Insulin production
Cloning
Creating genetically identical copy of an organism.
Dolly the sheep (1996) - First mammal cloned from adult cell
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